New drug cocktail shows promise for Tough-to-Treat lung cancer

NCT ID NCT05601973

First seen Jan 26, 2026 · Last updated May 10, 2026 · Updated 19 times

Summary

This study tests a combination of three drugs (amivantamab, lazertinib, and bevacizumab) in 60 people with advanced EGFR-mutant non-small cell lung cancer whose disease worsened after previous treatment. The goal is to see if adding two drugs to a standard targeted therapy can shrink tumors. This is not a cure, as patients require ongoing treatment to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AO SM Misericorida Perugia

    Perugia, Italy

  • Catalan Institute of Oncology

    L'Hospitalet de Llobregat, Spain

  • Centre Hospitalier d'Avignon

    Avignon, France

  • Centre Léon Bérard

    Lyon, France

  • Chu Angers

    Angers, France

  • Hospital Universitario Alicante Dr Balmis ISABIAL

    Alicante, Spain

  • Hospital Universitario Basurto

    Bilbao, Spain

  • Hospital Universitario Fundación Jiménez Díaz

    Madrid, Spain

  • Hospital Universitario de A Coruña

    A Coruña, Spain

  • Hospital clínico universitario de Valladolid

    Valladolid, Spain

  • Hôpitaux universitaires de Genève (HUG)

    Geneva, Switzerland

  • ICO Badalona

    Badalona, Spain

  • Istituto Oncologico della Svizzera Italiana

    Bellinzona, Switzerland

  • Kantonsspital St. Gallen

    Sankt Gallen, Switzerland

  • Netherlands Cancer Institute (NKI)

    Amsterdam, Netherlands

  • The Royal Marsden NHS Foundation Trust

    London, United Kingdom

  • Universitätsklinik für Medizinische Onkologie, Inselspital

    Bern, Switzerland

  • Vall d´Hebron University Hospital VHIO

    Barcelona, Spain

Conditions

Explore the condition pages connected to this study.