Race to stop Alzheimer's before it starts: new vaccine enters major trial

NCT ID NCT06544616

Ongoing Disease control Sponsor: Janssen Pharmaceutica N.V., Belgium Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an experimental vaccine can slow or prevent cognitive decline in people who have early Alzheimer's-related brain changes but no memory symptoms yet. About 500 participants will receive either the vaccine or a placebo and be followed for about 4 years to see if it helps maintain their thinking skills. The vaccine is designed to train the immune system to target a specific protein called tau that builds up in the Alzheimer's brain.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AMC Research, LLC

Matthews, North Carolina, 28105, United States
Alzheimers Research Australia

Nedlands, 6009, Australia
Alzheimers Research and Treatment Center

Stuart, Florida, 34997, United States
Alzheimers Research and Treatment Center

Wellington, Florida, 33414, United States
Artemis Institute for Clinical Research

Riverside, California, 92503, United States
Artemis Institute for Clinical Research

San Diego, California, 92123, United States
Austin Health Heidelberg Repatriation Hospital

Ivanhoe, 3079, Australia
Az Groeninge

Kortrijk, 8500, Belgium
Barcelona Beta Brain Research Center

Barcelona, 08005, Spain
Butler Hospital

Providence, Rhode Island, 02906, United States
CHRU Tours Hopital Bretonneau

Tours, 37000, France
CHU Pitie Salpetriere

Paris, 75013, France
CHU Toulouse - Hôpital La Grave

Toulouse, 31059, France
Centro At. Esp. Oroitu

Getxo, 48993, Spain
Charter Research

The Villages, Florida, 32162, United States
Clinica Univ. de Navarra

Pamplona, 31008, Spain
Clinical NeuroScience Solutions Inc

Jacksonville, Florida, 32256, United States
Clinical Trials of Texas Inc

San Antonio, Texas, 78229, United States
Enomoto Internal Medicine Clinic

Chofu-shi, 1820036, Japan
Esperanza Clinical

Murrieta, California, 92562, United States
Excel Medical Clinical Trials, LLC

Boca Raton, Florida, 33434, United States
Fund. Ace-Inst. Cat. Neuroc. Aplicades

Barcelona, 08028, Spain
Great Lakes Clinical Trials

Chicago, Illinois, 60640, United States
Great Lakes Clinical Trials

Gurnee, Illinois, 60031, United States
Hatsuta Neurology Clinic

Hirakata-shi, 573-1121, Japan
Hattiesburg Clinic

Hattiesburg, Mississippi, 39401, United States
Headlands Research Orlando

Orlando, Florida, 32806, United States
Higashi-Shinjuku Clinic

Shinjuku-ku, 169-0072, Japan
Hopital Lariboisiere-Fernand Widal

Paris, 75010, France
Hopital Nord Laennec CHU NANTES

Nantes, 44800, France
Hopital Roger Salengro - CHU Lille

Lille, 59037, France
Hosp Clinic de Barcelona

Barcelona, 08036, Spain
Hosp. Clinico San Carlos

Madrid, 28040, Spain
Hosp. Mutua Terrassa

Terrassa, 08222, Spain
Hosp. Quiron Madrid Pozuelo

Pozuelo de Alarcón, 28223, Spain
Hosp. Univ. Santa Maria

Lleida, 25198, Spain
Hosp. Viamed Montecanal

Zaragoza, 50012, Spain
Idc Salud Hosp. Gral. de Catalunya

Sant Cugat del Vallès, 08190, Spain
Irvine Clinical Research

Irvine, California, 92614, United States
JEM Research LLC

Atlantis, Florida, 33462, United States
Jinsenkai MI Clinic

Toyonaka-shi, 5600004, Japan
K2 Medical Research

Lady Lake, Florida, 32159, United States
K2 Medical Research

Maitland, Florida, 32751, United States
K2 Medical Research

Tampa, Florida, 33634, United States
K2 Medical Research Winter Garden

Clermont, Florida, 34711, United States
KaRa Institute of Neurological Diseases

Macquarie Park, 2113, Australia
Karolinska Universitetssjukhuset Huddinge

Stockholm, 14186, Sweden
Keystone Clinical Studies LLC

Plymouth Meeting, Pennsylvania, 19462, United States
Kings College Hospital

London, WC2R 2LS, United Kingdom
Kobe City Medical Center General Hospital

Kobe, 650 0047, Japan
Kusunoki Clinic

Kobe, 650-0044, Japan
Medical corporation Shinanokai Samoncho Clinic

Shinjyuku Ku, 160 0017, Japan
Memory Clinic Inc

Bennington, Vermont, 05201, United States
Merritt Island Medical Research, LLC

Merritt Island, Florida, 32952, United States
Moorgreen Hospital Memory Assessment And Research Centre

Southampton, S03 3JB, United Kingdom
Musashimurayama Hospital

Musashimurayama, 208-0022, Japan
Nagomi Clinic

Toyonaka-shi, 560-0004, Japan
Neuro Trials Victoria

Carlton, 3053, Australia
Neurological Associates of Albany, PC

Albany, New York, 12208, United States
OCROM Clinic

Suita Shi, 565 0853, Japan
Palm Beach Neurology and Premier Research Institute

West Palm Beach, Florida, 33407, United States
Quest Research Institute

Farmington Hills, Michigan, 48334, United States
Re-Cognition Health

Birmingham, B16 8LT, United Kingdom
Re-Cognition Health

Bristol, BS32 4SY, United Kingdom
Re-Cognition Health

Guildford, GU2 7YD, United Kingdom
Re-Cognition Health

London, W1G 8TA, United Kingdom
Re-Cognition Health

Plymouth, PL6 8BT, United Kingdom
Re-Cognition Health

Winchester, SO23 8SR, United Kingdom
Royal United Hospital

Bath, BA1 3NG, United Kingdom
Saiseikai Narashino Hospital

Narashino-shi, 275-8580, Japan
Scottish Brain Sciences

Edinburgh, EH12 5PJ, United Kingdom
Skanes universitetssjukhus

Malmo, 20502, Sweden
Southampton General Hospital

Southampton, SO16 6YD, United Kingdom
Southern Neurology

Kogarah, 2217, Australia
St Vincent's Centre for Applied Medical Research

Darlinghurst, 2010, Australia
The Cognitive and Research Center of New Jersey LLC

Springfield, New Jersey, 07081, United States
The Medical Research Network, LLC

New York, New York, 10128, United States
The Prince Charles Hospital

Chermside, 4032, Australia
ToCROM Clinic

Shinjuku Ku, 160 0008, Japan
Tokyo Asbo Clinic

Chūōku, 104-0031, Japan
Universitaetsklinikum Koeln

Cologne, 50937, Germany
Universitaetsklinikum der RWTH Aachen

Aachen, 52074, Germany
Universitaetsklinikum des Saarlandes

Homburg, 66421, Germany
Universitatsklinikum Munster

Münster, 48149, Germany
University of Oxford

Oxford, OX3 7JX, United Kingdom
University of Virginia

Charlottesville, Virginia, 22903, United States
Valley Medical Research

Centerville, Ohio, 45459-2785, United States
Velocity Clinical Research

East Syracuse, New York, 13057, United States
Xenoscience Inc.

Phoenix, Arizona, 85004, United States
Yale University School Of Medicine

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

PRECLINICAL ALZHEIMER'S DISEASE