New pill targets Alzheimer's in High-Risk gene carriers

NCT ID NCT04693520

First seen Jan 10, 2026 · Last updated Jun 13, 2026 · Updated 25 times

Summary

This study tested an oral drug called ALZ-801 in 84 people with early Alzheimer's who carry the APOE4 gene variant, which increases risk. Researchers measured changes in blood and brain scan markers of Alzheimer's over 65 weeks to see if the drug slows disease progression. The goal was to evaluate safety and effects on key Alzheimer's-related proteins.

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Contacts and locations

Locations

  • Brain Research Center

    's-Hertogenbosch, Netherlands

  • Brain Research Center

    Amsterdam, Netherlands

  • Brain Research Center

    Zwolle, Netherlands

  • Motol University Hospital

    Prague, Czechia

  • St. Anne's University Hospital

    Brno, Czechia

  • Vestra Clinics

    Rychnov nad Kněžnou, Czechia

Conditions

Explore the condition pages connected to this study.