Alzheimer's pill targets brain plaques in High-Risk patients

NCT ID NCT04693520

Summary

This study tested whether an oral medication called ALZ-801 could affect biological markers of Alzheimer's disease in people with early symptoms who carry specific genetic risk factors (APOE4 gene). The 84 participants took the pill twice daily for up to four years while researchers measured changes in blood and brain scan markers related to Alzheimer's progression. The main goals were to see if the treatment was safe and whether it affected key Alzheimer's biomarkers like tau protein and brain shrinkage.

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Contacts and locations

Locations

  • Brain Research Center

    's-Hertogenbosch, Netherlands

  • Brain Research Center

    Amsterdam, Netherlands

  • Brain Research Center

    Zwolle, Netherlands

  • Motol University Hospital

    Prague, Czechia

  • St. Anne's University Hospital

    Brno, Czechia

  • Vestra Clinics

    Rychnov nad Kněžnou, Czechia

Conditions

Explore the condition pages connected to this study.