New Alzheimer's pill shows promise in slowing cognitive decline for High-Risk group

NCT ID NCT04770220

Completed Disease control Sponsor: Alzheon Inc. Source: ClinicalTrials.gov ↗

Summary

This Phase 3 trial tested whether an oral medication called ALZ-801 could slow Alzheimer's progression in people with early-stage disease who carry two copies of the APOE4 gene, which increases risk. 325 participants took either the drug or a placebo twice daily for 78 weeks while researchers measured changes in memory, thinking, and daily living skills. The study aimed to see if ALZ-801 could help control disease progression rather than provide a cure, as treatment would need to continue.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

ALZ Research and Treatment Center (A.R.T.C.)

Stuart, Florida, 34997, United States
ALZ Research and Treatment Center (A.R.T.C.)

Wellington, Florida, 33414, United States
AMC Research

Matthews, North Carolina, 28105, United States
ATP Clinical Research

Costa Mesa, California, 92626, United States
Abington Neurological Associates

Abington, Pennsylvania, 19001, United States
Advanced Memory Research Center

Toms River, New Jersey, 08755, United States
Advanced Research Consultants

Palm Beach Gardens, Florida, 33410, United States
Alphab Global Research

Jupiter, Florida, 33458, United States
Aqualane Clinical Research

Naples, Florida, 34105, United States
Banner Sun Health Research Institute

Sun City, Arizona, 85351, United States
Bradenton Research Center

Bradenton, Florida, 34205, United States
Brain Research Center Amsterdam

Amsterdam, 1081 GN, Netherlands
Brain Research Center Den Bosch

's-Hertogenbosch, 5223 LA, Netherlands
Brain Research Center Zwolle

Zwolle, 8025 AZ, Netherlands
CCT Research

Scottsdale, Arizona, 85297, United States
Center for Cognitive Health

Portland, Oregon, 97225, United States
Centre Hospitalier Universitaire (CHU) Hopitaux de Rouen

Rouen, 76031, France
Centre Hospitalier Universitaire de Marseille - Hôpital de la Timone

Marseille, 13385, France
Centre de Recherche Clinique du Gerontopole - CHU Toulouse

Toulouse, 31059, France
Centre de Recherche-Hopital Geriatrique de Charpennes

Villeurbanne, 69100, France
Centricity Research

Halifax, Nova Scotia, B3S 1N2, Canada
Centricity Research

New Minas, Nova Scotia, B4N 3R7, Canada
Centro Hospital Universitario Dr. Preset

Valencia, 46017, Spain
Charter Research

Lady Lake, Florida, 32159, United States
Charter Research

Orlando, Florida, 32803, United States
Clinica Universidad de Navarra

Madrid, 28027, Spain
Clinica Universidad de Navarra

Pamplona, 31008, Spain
Collaborative NeuroScience Network LLC

Long Beach, California, 90806, United States
Columbus Memory Center

Columbus, Georgia, 31909, United States
Fakultní nemocnice u sv. Anny v Brně (St. Anne's University Hospital)

Brno, 656 91, Czechia
Fort Wayne Neurological Center

Fort Wayne, Indiana, 46804, United States
Fundacia ACE - Institut Catala de Neurociencies Aplicadas

Barcelona, 08028, Spain
Galiz Research

Hialeah, Florida, 33016, United States
Headlands Research Eastern MA

Plymouth, Massachusetts, 02360, United States
Headlands Research Orlando

Orlando, Florida, 32819, United States
Hopital Gui de Chauliac - CHRU de Montpellier

Montpellier, 43431, France
Hopital Lariboisiere - Fernand-Widal - AP-HP

Paris, 75475, France
Hopitaux Universitaires de Strasbourg Centre d'Investigation Clinique

Strasbourg, 67200, France
Hospital Clinico San Carlos

Madrid, 28040, Spain
Hospital Universitari MutuaTerrassa

Terrassa, 08221, Spain
IPS Research

Oklahoma City, Oklahoma, 73106, United States
JEM Research Institute, Headlands Site

Atlantis, Florida, 33462, United States
K2 Medical Research, LLC

Maitland, Florida, 32751, United States
Kawartha Centre - Redefining Healthy Aging

Peterborough, Ontario, K9H 2P4, Canada
Kline Institute for Psychiatric Research

Orangeburg, New York, 10962, United States
Klinikum der Universitaet Muenchen Innenstadt

München, 80336, Germany
Lehigh Center for Clinical Research

Allentown, Pennsylvania, 18104, United States
Louisiana State University Health Sciences Center (LSUHSC)

Shreveport, Louisiana, 71103, United States
Medica 111, Spol. s r.o. - Neurologicka a Rehabilitacni Ambulance Brno, Centralni Pracoviste v Brne

Brno, 602 00, Czechia
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Memory Clinic, Landspitali University Hospital

Reykjavik, 101, Iceland
Miami Jewish Health

Miami, Florida, 33137, United States
Mount Sinai Medical Center

Miami Beach, Florida, 33140, United States
NYU Alzheimer's Disease Research Center

New York, New York, 10016, United States
NeuroClin Glasgow Ltd

Motherwell, North Lanarkshire, ML1 4UF, United Kingdom
NeuroScience Research Center

Canton, Ohio, 44718, United States
Neurological Associates of Albany

Albany, New York, 12208, United States
Neurology Diagnostics, Inc.

Dayton, Ohio, 45459, United States
Neuropsychiatrie s.r.o.

Prague, 160 00, Czechia
Northwest Clinical Research Center

Bellevue, Washington, 98007, United States
OCT Research ULC (dba Okanagan Clinical Trials)

Kelowna, British Columbia, V1Y 1Z9, Canada
Premiere Research Institute

West Palm Beach, Florida, 33407, United States
Progressive Medical Research

Port Orange, Florida, 32127, United States
Quantum CNS Clinical Research

Pompano Beach, Florida, 33064, United States
Re-Cognition Health Ltd Birmingham

Birmingham, West Midlands, B16 8LT, United Kingdom
Re-Cognition Health Ltd Guildford

Guildford, Surrey, GU2 7YD, United Kingdom
Re-Cognition Health Ltd London

London, Greater London, W1G 9JF, United Kingdom
Re-Cognition Health Ltd Plymouth

Plymouth, Devon, PL6 8BT, United Kingdom
Re-Cognition Health Ltd Winchester

Winchester, SO21 1HU, United Kingdom
Re:Cognition Health

Fairfax, Virginia, 22031, United States
Re:Cognition Health Ltd Bristol

Bristol, BS32 4SY, United Kingdom
Recherches Neuro-Hippocampe Inc. d/b/a Clinique de la Mémoire de l'Outaouais

Gatineau, Quebec, J8T 8J1, Canada
Recherches Neuro-Hippocampe Inc., d/b/a Ottawa Memory Clinic

Ottawa, Ontario, K1Z 1G3, Canada
Rhode Island Mood & Memory Research Institute

East Providence, Rhode Island, 02914, United States
Richmond Behavioral Associates

Staten Island, New York, 10312, United States
SC3 Research Group

Pasadena, California, 91105, United States
Sandhill Research, LLC

Decatur, Georgia, 30030, United States
St. Pancras Clinical Research

London, EC2Y 8EA, United Kingdom
Stanford University

Palo Alto, California, 94304, United States
Studienzentrum Nord-West

Westerstede, 26655, Germany
Sutter Health

Sacramento, California, 95816, United States
Tilda Research

Irvine, California, 92780, United States
Toronto Memory Program

Toronto, Ontario, M3B 2S7, Canada
Torrance Clinical Research Institute

Lomita, California, 90717, United States
Triad Clinical Trials

Greensboro, North Carolina, 27410, United States
UCSD Shiley-Marcos Alzheimer's Disease Research Center

La Jolla, California, 92037, United States
UT Health Science Center at Houston

Houston, Texas, 77054, United States
University Hospital RWTH Aachen Neurological Study Center

Aachen, 52074, Germany
University of Rochester Medical Center

Rochester, New York, 14620, United States
Universitätsklinik fuer Psychiatrie und Psychotherapie

Tübingen, 72076, Germany
Vanderbilt Center for Cognitive Medicine

Nashville, Tennessee, 37212, United States
Vestra Clinics - Dedicated Research Clinics

Rychnov nad Kněžnou, 51601, Czechia
WR-CRCN

Las Vegas, Nevada, 89106, United States
Xenoscience

Phoenix, Arizona, 85004, United States
Y & L Advance Health Care, Inc /DBA Elite Clinical Research

Miami, Florida, 33144, United States

Conditions

Explore the condition pages connected to this study.

EARLY ALZHEIMER'S DISEASE