New drug trial aims to control debilitating Muscle-Weakening disease

NCT ID NCT05556096

Ongoing Disease control Sponsor: Alexion Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an investigational drug called ALXN1720 is safe and effective for adults with generalized myasthenia gravis, a chronic autoimmune disease that causes severe muscle weakness. About 261 participants will receive either the drug or a placebo for 26 weeks to see if it improves their ability to perform daily activities and reduces muscle weakness. The goal is to provide better control of the disease for people who have specific antibodies driving their condition.

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Contacts and locations

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Locations

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Orange, California, 92868, United States
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Fort Collins, Colorado, 80528, United States
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Washington D.C., District of Columbia, 20007, United States
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Bradenton, Florida, 34209, United States
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Maitland, Florida, 32751, United States
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Tampa, Florida, 33612, United States
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Augusta, Georgia, 30912, United States
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Gainesville, Georgia, 30501, United States
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Savannah, Georgia, 31406, United States
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Springfield, Illinois, 62769, United States
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Kansas City, Kansas, 66160, United States
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Lexington, Kentucky, 40503, United States
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Detroit, Michigan, 48202, United States
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East Lansing, Michigan, 48824, United States
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Las Vegas, Nevada, 89117, United States
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Patchogue, New York, 11772, United States
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Rochester, New York, 14620, United States
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Syracuse, New York, 13202, United States
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Chapel Hill, North Carolina, 27599, United States
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North Charleston, South Carolina, 29406, United States
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Houston, Texas, 77030, United States
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Richmond, Virginia, 23298, United States
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Morgantown, West Virginia, 26506, United States
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CABA, C1192AAW, Argentina
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Ciudad de Buenos Aires, 1015, Argentina
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Ciudad de Buenos Aires, 1181, Argentina
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Ciudad de Buenos Aires, AR-CP 1221, Argentina
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Rosario, S2000BZL, Argentina
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Innsbruck, 6020, Austria
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Wels, 4600, Austria
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Barretos, 14784-400, Brazil
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Joinville, 89202-190, Brazil
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Porto Alegre, 90620-130, Brazil
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Ribeirão Preto, 14051-140, Brazil
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Salvador, 41253-190, Brazil
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São José do Rio Preto, 15090-000, Brazil
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São Paulo, 05403-010, Brazil
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Edmonton, Alberta, T6G 2G3, Canada
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Toronto, Ontario, M5G 2C4, Canada
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Québec, Quebec, G1J 1Z4, Canada
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Beijing, 100034, China
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Beijing, 100730, China
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Changchun, 130021, China
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Changsha, 410008, China
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Chengdu, 610041, China
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Fuzhou, 350001, China
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Hangzhou, 310003, China
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Hangzhou, 310016, China
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Jinan, 250014, China
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Qingdao, 266035, China
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Shanghai, 200040, China
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Suzhou, 215006, China
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Wuhan, 430030, China
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Xi'an, 710000, China
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Aalborg, 9000, Denmark
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Copenhagen, 2100, Denmark
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Garches, 92380, France
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Lille, 59037, France
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Marseille, 13385, France
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Nice, 06000, France
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Paris, 75651, France
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Strasbourg, 67098, France
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Berlin, 10117, Germany
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Düsseldorf, 40225, Germany
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München, 81675, Germany
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Würzburg, 97074, Germany
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Hadera, 38100, Israel
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Haifa, 3109601, Israel
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Petah Tikva, 4910000, Israel
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Bergamo, 24127, Italy
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Brescia, 25123, Italy
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Florence, 50139, Italy
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Milan, 20133, Italy
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Naples, 80131, Italy
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Palermo, 90127, Italy
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Pisa, 56126, Italy
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Roma, 00168, Italy
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Rome, 00189, Italy
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Chiba, 260-8677, Japan
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Fukushima, 960-1295, Japan
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Higashimatsuyama-shi, 355-0005, Japan
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Isehara-shi, 259-1193, Japan
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Itabashi-ku, 173-8610, Japan
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Kawasaki-shi, 216-8511, Japan
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Morioka, 020-8505, Japan
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Nagasaki, 852-8501, Japan
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Nagoya, 466-0065, Japan
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Nagoya, 467-0001, Japan
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Shinjuku-ku, 160-0023, Japan
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Shinjuku-ku, 160-8582, Japan
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Suita-shi, 565-0871, Japan
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Amsterdam, 1105 AZ, Netherlands
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Bydgoszcz, 85-086, Poland
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Katowice, 40-689, Poland
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Krakow, 31-202, Poland
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Krakow, 31-505, Poland
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Lublin, 20064, Poland
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Poznan, 61-731, Poland
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Almada, 2805-267, Portugal
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Porto, 4099-001, Portugal
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Belgrade, 11000, Serbia
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Niš, 18000, Serbia
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Busan, 49241, South Korea
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Daegu, 41404, South Korea
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Gwangju, 61469, South Korea
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Seoul, 02841, South Korea
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Seoul, 03722, South Korea
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Seoul, 05505, South Korea
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Seoul, 06351, South Korea
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Seoul, 5030, South Korea
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Badalona (Barcelona), 08916, Spain
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Córdoba, 14004, Spain
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L'Hospitalet de Llobregat, 08907, Spain
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Madrid, 28034, Spain
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Madrid, 28040, Spain
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Madrid, 28046, Spain
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Madrid, 28702, Spain
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Málaga, 29010, Spain
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Seville, 41009, Spain
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Sankt Gallen, CH-9007, Switzerland
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Kaohsiung City, 833401, Taiwan
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New Taipei City, 23561, Taiwan
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Tainan, 70403, Taiwan
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Taipei, 11101, Taiwan
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Bursa, 16059, Turkey (Türkiye)
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Istanbul, 34452, Turkey (Türkiye)
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Kocaeli, 41380, Turkey (Türkiye)
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Samsun, 55139, Turkey (Türkiye)
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Liverpool, L9 7AL, United Kingdom
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London, EC1A 7BE, United Kingdom
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Oxford, 0X3 7LE, United Kingdom
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Sheffield, S10 2JF, United Kingdom

Conditions

Explore the condition pages connected to this study.

GENERALIZED MYASTHENIA GRAVIS