Experimental drug targets Cancer's internal brakes in patients out of options

NCT ID NCT02264613

Summary

This early-stage trial tested a new drug called ALRN-6924, alone or with another cancer drug, in 142 adults with advanced solid tumors or lymphomas that had stopped responding to standard treatments. The main goals were to find a safe dose and see if the drug could shrink tumors in patients whose cancers have a specific genetic feature called wild-type p53. The study was completed to gather initial safety and effectiveness data.

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Contacts and locations

Locations

  • Study site

    Birmingham, Alabama, 35294, United States

  • Study site

    Duarte, California, 91010, United States

  • Study site

    Denver, Colorado, 80218, United States

  • Study site

    Sarasota, Florida, 34232, United States

  • Study site

    Tampa, Florida, 33612, United States

  • Study site

    Boston, Massachusetts, 02114, United States

  • Study site

    Boston, Massachusetts, 02215, United States

  • Study site

    New York, New York, 10065, United States

  • Study site

    The Bronx, New York, 10461, United States

  • Study site

    Greenville, South Carolina, 29605, United States

  • Study site

    Nashville, Tennessee, 37203, United States

  • Study site

    Houston, Texas, 77030, United States

  • Study site

    Seattle, Washington, 98105, United States

Conditions

Explore the condition pages connected to this study.