New drug duo targets deadly brain TB in early trial

NCT ID NCT07350174

First seen Jan 28, 2026 · Last updated May 08, 2026 · Updated 15 times

Summary

This study tests a new two-drug combination (Alpibectir and Ethionamide) added to standard treatment for tuberculosis meningitis, a serious brain infection. About 64 adults with newly diagnosed TB meningitis will receive either the new combo or standard care. The main goal is to measure how much drug reaches the blood and spinal fluid, and to check for side effects.

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