Aloe vera gel may heal Children's burns as well as standard cream, trial hopes

NCT ID NCT07716605

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether aloe vera gel can heal superficial burns in children as effectively as the standard treatment, silver sulfadiazine cream. About 60 children aged 1 to 18 with minor burns will receive either aloe vera gel or the cream applied three times daily. Researchers will track how quickly the burns heal, pain levels, infection rates, and scarring over two weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aloe vera gel and silver sulfadiazine cream
What this could lead to
If aloe vera gel works as well or better than standard silver sulfadiazine, it could offer a more natural, less painful option for treating children's burns.
What could go wrong
This is a small, early-stage trial with only 60 children, so results may not apply to larger or deeper burns. Aloe vera may not prevent infection as effectively as the standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Feb 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

1 day to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \- Patients aged 1 to 18 years * Both male and female patients * Superficial and superficial partial-thickness burns * Burn extent involving 1% to 25% total body surface area (TBSA) * Presentation within acute phase of burn injury Exclusion Criteria: * \- Deep partial-thickness (deep second-degree) or third-degree burns * Patients requiring surgical intervention (skin grafting) * Infected burns at presentation * Patients with major comorbidities affecting wound healing (e.g., immunodeficiency, diabetes mellitus) * Known hypersensitivity to Aloe vera or silver sulfadiazine

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UCHSLahore

    Lahore, Punjab Province, 54000, Pakistan