New drug aims to tame rare bleeding disorder

NCT ID NCT06659640

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 31 times

Summary

This study tests a new medicine called ALN-6400 for people with hereditary hemorrhagic telangiectasia (HHT), a condition that causes abnormal blood vessels and frequent nosebleeds. The trial first checks safety in healthy volunteers, then tests how well the drug controls symptoms in HHT patients. It is a phase 1/2 study, meaning it is early-stage research focused on safety and initial effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Trial Site

    RECRUITING

    Birmingham, Alabama, 35233, United States

  • Clinical Trial Site

    RECRUITING

    Cypress, California, 90630, United States

  • Clinical Trial Site

    RECRUITING

    Gainesville, Florida, 32608, United States

  • Clinical Trial Site

    RECRUITING

    Indianapolis, Indiana, 46260, United States

  • Clinical Trial Site

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Clinical Trial Site

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Clinical Trial Site

    RECRUITING

    St Louis, Missouri, 63110, United States

  • Clinical Trial Site

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • Clinical Trial Site

    RECRUITING

    Camperdown, 2050, Australia

  • Clinical Trial Site

    RECRUITING

    Parkville, 3050, Australia

  • Clinical Trial Site

    RECRUITING

    Mount Royal, H3P 3P1, Canada

  • Clinical Trial Site

    RECRUITING

    Toronto, M5B 1W8, Canada

  • Clinical Trial Site

    RECRUITING

    Bordeaux, 33000, France

  • Clinical Trial Site

    RECRUITING

    Bron, 69500, France

  • Clinical Trial Site

    RECRUITING

    Homburg, 66421, Germany

  • Clinical Trial Site

    RECRUITING

    L'Hospitalet de Llobregat, 8907, Spain

Conditions

Explore the condition pages connected to this study.