New blood test could spot cancer return after transplant
NCT ID NCT04635384
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a new blood test called AlloHeme that measures how much of a patient's own cells remain after a bone marrow transplant. The goal is to see if this test can predict whether the cancer (acute leukemia or myelodysplastic syndrome) will come back. About 307 adults who are getting a transplant will provide blood and bone marrow samples before and after the procedure. The test looks at tiny amounts of leftover patient cells, which might signal a higher risk of relapse.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AlloHeme test (a blood test using next-generation sequencing to measure donor and recipient cells)
What this could lead to
If successful, this test could help doctors detect relapse earlier after transplant, potentially improving treatment timing and outcomes.
What could go wrong
This is an observational study, not a treatment trial. The test may not reliably predict relapse, and results may not apply to all patients or transplant types.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACUTE LYMPHOBLASTIC LEUKEMIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
City of Hope
Duarte, California, 91010, United States
-
Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
-
Columbia University Irving Medical Center
New York, New York, 10032, United States
-
Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
-
Georgia Cancer Center at Augusta University
Augusta, Georgia, 30912, United States
-
H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, 33612, United States
-
Oregon Health & Science University
Portland, Oregon, 97239, United States
-
University of California Irvine
Brisbane, California, 94005, United States
-
University of Utah
Salt Lake City, Utah, 84112, United States
-
Washington University in St. Louis
St Louis, Missouri, 63110, United States