Off-the-Shelf CAR t cells show promise for tough lymphomas
NCT ID NCT03939026
First seen Nov 05, 2025 · Last updated May 15, 2026 · Updated 28 times
Summary
This early-phase study tested a new type of cancer treatment called ALLO-501, which is a 'off-the-shelf' CAR T cell therapy made from donor cells. It was given to 50 adults with large B-cell lymphoma or follicular lymphoma that had come back or stopped responding to at least two prior treatments. The goal was to check the treatment's safety and how well it worked, using a special drug (ALLO-647) to help prepare the body. While not a cure, this approach aims to control the disease without needing lifelong medication.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Banner MD Anderson Cancer Center
Gilbert, Arizona, 85234, United States
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Colorado Blood Cancer Institute
Denver, Colorado, 80218, United States
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MD Anderson
Houston, Texas, 77030, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Norton Cancer Institute
Louisville, Kentucky, 40207, United States
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St. Davids South Austin Medical Center
Austin, Texas, 78704, United States
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Stanford University
Stanford, California, 94305, United States
Conditions
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