Experimental cell therapy targets Hard-to-Treat kidney cancer

NCT ID NCT04696731

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 29 times

Summary

This early-phase study tests an experimental cell therapy called ALLO-316 in adults with advanced or metastatic clear cell kidney cancer who have already tried standard treatments. Participants receive the therapy after a short course of chemotherapy to prepare their immune system. The main goals are to check safety and find the best dose for future studies.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • UCLA Medical Center

    Los Angeles, California, 90095, United States

  • UCSF Medical Center

    San Francisco, California, 94143, United States

  • Yale School of Medicine

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.