New cell therapy takes on advanced kidney cancer

NCT ID NCT04696731

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tests a new treatment called ALLO-316 for people with advanced or spreading clear cell kidney cancer who have already tried standard therapies like checkpoint inhibitors and VEGF inhibitors. The treatment uses specially designed immune cells from a donor to attack the cancer, given after a short chemotherapy course to prepare the body. The main goals are to find the safest dose and see if it helps control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

clear cell renal carcinoma Clear-cell metastatic renal cell carcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • UCLA Medical Center

    Los Angeles, California, 90095, United States

  • UCSF Medical Center

    San Francisco, California, 94143, United States

  • Yale School of Medicine

    New Haven, Connecticut, 06520, United States