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New hope for kids with Tough-to-Treat tumors

NCT ID NCT04774718

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

Summary

This study is testing an oral drug called alectinib in children and teenagers with advanced solid or brain tumors that have a specific genetic change (ALK fusion) and have not responded to standard treatments. The main goals are to find a safe dose, see how the drug behaves in the body, and measure if it helps shrink the tumors. It is for young patients who have run out of other effective treatment options.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • Beijing Children's Hospital, Capital Medical University

    RECRUITING

    Beijing, 100045, China

  • CHU Sainte-Justine

    RECRUITING

    Montreal, Quebec, H3T 1C5, Canada

  • Centre Léon Bérard, Institut d?Hémato-Oncologie Pédiatrique

    RECRUITING

    Lyon, 69373, France

  • Children's Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55404, United States

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

  • Dipartimento di Scienze Pediatriche Adolescenza

    RECRUITING

    Turin, Piedmont, 10126, Italy

  • Graacc-Grupo de Apoio ao adolescente e a crianca com cancer

    RECRUITING

    São Paulo, São Paulo, 04038-030, Brazil

  • Great North Children's Hospital

    RECRUITING

    Newcastle upon Tyne, NE1 4LP, United Kingdom

  • Great Ormond Street Hospital

    RECRUITING

    London, WC1N 3JH, United Kingdom

  • Hospital Infantil Universitario Nino Jesus

    RECRUITING

    Madrid, 28009, Spain

  • Hospital Universitari i Politecnic La Fe

    RECRUITING

    Valencia, 46026, Spain

  • Hospital Universitario Virgen del Rocio

    RECRUITING

    Seville, 41 41013, Spain

  • Hospital de Cancer de Barretos

    RECRUITING

    Barretos, São Paulo, 14784-400, Brazil

  • Hôpital de la Timone, Oncologie Pédiatrique

    RECRUITING

    Marseille, 13385, France

  • Institut Curie - Centre de Lutte Contre le Cancer (CLCC) de Paris

    RECRUITING

    Paris, 75248, France

  • Istituto Giannina Gaslini-Ospedale Pediatrico IRCCS

    ACTIVE_NOT_RECRUITING

    Genoa, Liguria, 16147, Italy

  • Istituto Nazionale Tumori di Milano

    RECRUITING

    Milan, Lombardy, 20133, Italy

  • Johns Hopkins All Children's Hospital

    RECRUITING

    St. Petersburg, Florida, 33701, United States

  • Lucile Packard Children's Hospital

    RECRUITING

    Palo Alto, California, 94304, United States

  • Memorial Sloan Kettering Cancer Center

    ACTIVE_NOT_RECRUITING

    New York, New York, 10065, United States

  • Rigshospitalet

    RECRUITING

    København Ø, 2100, Denmark

  • Royal Children's Hospital

    RECRUITING

    Parkville, Victoria, 3052, Australia

  • Royal Manchester Childrens Hospital

    RECRUITING

    Manchester, M13 9WL, United Kingdom

  • Royal Marsden Hospital (Sutton)

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • St. Jude Children'S Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

  • Sydney Children's Hospital

    RECRUITING

    Randwick, New South Wales, 2031, Australia

  • The Hospital for Sick Children

    RECRUITING

    Toronto, Ontario, M5G 1X8, Canada

  • University of Michigan, C.S. Mott Children's Hospital

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • Universitätsklinikum Heidelberg

    WITHDRAWN

    Heidelberg, 69120, Germany

  • Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, 200092, China

Conditions

Explore the condition pages connected to this study.

ALK FUSION-POSITIVE SOLID OR CNS TUMORS