New hope for rare disease: enzyme therapy studied in china

NCT ID NCT05134571

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 21 times

Summary

This study looked at the safety and effectiveness of Aldurazyme (laronidase) in 12 Chinese people with MPS I, a rare genetic disorder. Participants received weekly infusions for 26 weeks. The main goals were to track side effects and measure changes in urinary GAGs (a marker of disease) and liver size.

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Contacts and locations

Locations

  • Investigational Site Number :1560001

    Wuhan, 430030, China

  • Investigational Site Number :1560002

    Beijing, 100730, China

  • Investigational Site Number :1560003

    Beijing, 100034, China

  • Investigational Site Number :1560004

    Guangzhou, 510623, China

  • Investigational Site Number :1560006

    Hangzhou, 310003, China

Conditions

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