Could a common dewormer stop a rare, deadly liver parasite?

NCT ID NCT07182305

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This Phase 2 trial tested the drug albendazole in 194 people with early-stage alveolar echinococcosis, a parasitic liver disease that is nearly always fatal within 10-15 years if untreated. Participants took albendazole twice daily and were monitored with ultrasound to see if their liver lesions shrank, calcified, or stopped growing. The goal is to see if early treatment can control the parasite and extend life.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
albendazole
What this could lead to
If successful, this could confirm that early albendazole treatment controls the parasite and prevents disease progression, potentially allowing patients to live a normal lifespan.
What could go wrong
This is a small, completed Phase 2 trial in one region. Albendazole is parasitostatic, not curative, and lifelong treatment may be needed. Results may not apply to other populations.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of disease prevention and sanitary - epidemiological surveillance

    Bishkek, Kyrgyzstan