New Dual-Action drug shows promise in advanced lung cancer trial

NCT ID NCT04900363

First seen Mar 04, 2026 · Last updated May 11, 2026 · Updated 9 times

Summary

This trial tested a new drug called AK112 in 108 people with advanced non-small cell lung cancer (stage IIIB/C or IV) whose tumors had a PD-L1 score of 1% or higher. The drug is a bispecific antibody that targets both PD-1 and VEGF to help the immune system fight cancer and block tumor blood supply. The main goals were to see how many patients' tumors shrank or disappeared, how long that lasted, and to check for side effects.

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Contacts and locations

Locations

  • Shanghai Pulmonary Hospital

    Shanghai, Shanghai Municipality, 200433, China

Conditions

Explore the condition pages connected to this study.