New hope for lung cancer patients who stop responding to standard therapy

NCT ID NCT05184712

First seen Mar 21, 2026 · Last updated May 01, 2026 · Updated 5 times

Summary

This study tests whether adding the experimental drug AK112 to standard chemotherapy can help people with a specific type of advanced lung cancer (EGFR-mutant non-squamous NSCLC) live longer without their cancer growing. Participants have already tried and failed an EGFR-targeted pill. About 322 adults will receive either AK112 or a placebo, plus chemo, to see if the combination improves outcomes like progression-free survival and overall survival.

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Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510000, China

Conditions

Explore the condition pages connected to this study.