New hope for lung cancer patients whose first treatment failed

NCT ID NCT05184712

First seen Mar 21, 2026 · Last updated Jun 09, 2026 · Updated 12 times

Summary

This study tests whether adding the experimental drug AK112 to standard chemotherapy can help people with a specific type of advanced lung cancer (EGFR-mutant non-squamous NSCLC) whose initial targeted therapy stopped working. About 322 participants will receive either AK112 or a placebo, plus two chemotherapy drugs. The main goal is to see if the combination delays cancer growth.

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Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510000, China

Conditions

Explore the condition pages connected to this study.