New hope for aggressive colon cancer: targeted drug AK104 tested before surgery

NCT ID NCT07412613

First seen Feb 18, 2026 · Last updated May 16, 2026 · Updated 9 times

Summary

This study tests a new drug called AK104 (Cadonilimab) given before and after surgery for people with a specific type of colon cancer (MSI-H/dMMR) that can be removed. The goal is to see if AK104 works better than standard chemotherapy at shrinking the tumor and preventing the cancer from coming back. About 386 adults aged 18-75 with stage IIB-III colon cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.