New hope for myelofibrosis patients who fail current therapies
NCT ID NCT06343805
First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 30 times
Summary
This early-stage study tests an experimental pill, AJ1-11095, in people with a bone marrow cancer called myelofibrosis. Participants must have already tried a standard JAK2 inhibitor without success. The main goals are to check the drug's safety and find the best dose for future studies.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AP-HP Hopital Saint-Louis
RECRUITINGParis, France
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-••••
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David H. Koch Center for Cancer Care at Memorial Sloan Kettering
RECRUITINGNew York, New York, 10021, United States
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
NOT_YET_RECRUITINGMilan, Italy, Italy
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Genesis Cancer Care UK Limited - Oxford
NOT_YET_RECRUITINGOxford, UK, United Kingdom
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Guy's Hospital
NOT_YET_RECRUITINGLondon, UK, United Kingdom
Contact Phone: •••-•••-••••
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Hospital Clinic Barcelona
RECRUITINGBarcelona, Spain
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Hospital General Universitario Gregorio Maranon
RECRUITINGMadrid, Spain, Spain
Contact Phone: •••-•••-••••
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Hospital Universitario Ramon y Cajal
RECRUITINGMadrid, Spain
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IRCCS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant Orsola
NOT_YET_RECRUITINGBologna, Italy, Italy
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
Contact Phone: •••-•••-••••
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Levine Cancer Institute
RECRUITINGCharlotte, North Carolina, 28204, United States
Contact Phone: •••-•••-••••
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-••••
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-••••
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Moffitt Cancer Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact Phone: •••-•••-••••
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Stanford Cancer Institute
RECRUITINGPalo Alto, California, 94304, United States
Contact Phone: •••-•••-••••
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The Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
Contact Phone: •••-•••-••••
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University of Cincinnati
RECRUITINGCincinnati, Ohio, 45221, United States
Contact Phone: •••-•••-••••
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-••••
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-••••
Conditions
Explore the condition pages connected to this study.