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AI dentists? chatbots take on root canal diagnosis

NCT ID NCT07706894

Diagnosis Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests whether three advanced AI chatbots — ChatGPT, Gemini, and Claude — can accurately diagnose tooth infections and assess how difficult a root canal treatment will be. Researchers will compare the AI's answers to those of a panel of endodontic experts using real patient records. The goal is to see if these AI tools could serve as reliable decision-support aids for dentists.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Three educated large language models (ChatGPT, Gemini, Claude) used as diagnostic tools
What this could lead to
If successful, this could show that AI chatbots can help dentists diagnose root canal problems more consistently, potentially reducing misdiagnosis and improving treatment planning.
What could go wrong
This is an early-stage diagnostic accuracy study, not a treatment trial. The AI may not perform as well as human experts in real-world settings, and results may not apply to other dental conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 349 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Eligible patients seeking primary endodontic treatment or retreatment

Ages

16 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age above 16 years old. 2. Requiring primary endodontic treatment or retreatment. 3. Availability of complete clinical examination records. 4. Availability of diagnostic radiographs. 5. Restorable teeth. 6. Patient's acceptance to participate in the study. Exclusion Criteria: 1. Incomplete records 2. Pregnant women. 3. No restorability: Hopeless tooth. 4. Traumatic dental injuries 5. Periapical radiographic images of sub-optimal quality or artifacts/high scatter interfering with proper assessment.

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Conditions

The condition(s) this trial relates to.

Periapical Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pulpal and periapical diseases

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

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