AI predicts lymphedema risk to guide breast cancer radiation decisions

NCT ID NCT07187726

Recruiting now Knowledge-focused Sponsor: UNICANCER Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether an artificial intelligence tool can predict a breast cancer patient's risk of developing arm lymphedema (swelling) after radiation therapy. About 724 women will be randomly assigned to either see their personalized risk prediction or not. The goal is to see if knowing this risk helps patients and doctors choose safer radiation options, reducing side effects and improving quality of life over two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AI-based risk prediction tool (XAINET)
What this could lead to: If successful, this could help breast cancer patients and doctors make more informed decisions about radiotherapy, potentially reducing arm swelling and improving quality of life.
What could go wrong: This is a study about communication, not a new treatment. The AI tool's predictions may not be accurate for everyone, and the trial is still recruiting, so results are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast neoplasm invasive breast carcinoma Unilateral Breast Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

UNILATERAL BREAST NEOPLASMS

Contacts and locations

Locations

CH Lyon Sud
RECRUITING

Oullins, France
CH de Saint Quentin
RECRUITING

Saint-Quentin, France
CHD Vendée
RECRUITING

La Roche-sur-Yon, France
CHI Créteil
RECRUITING

Créteil, France
CHU Sud La Réunion
RECRUITING

Saint-Pierre, France
Centre Antoine Lacassagne
RECRUITING

Nice, France
Centre François Baclesse
RECRUITING

Caen, France
Centre Georges François Leclerc
RECRUITING

Dijon, France
Centre Guillaume Le Conquérant
RECRUITING

Le Havre, France
Centre Henri Becquerel
RECRUITING

Rouen, France
Centre Jean Perrin
RECRUITING

Clermont-Ferrand, France
Centre Léon Bérard
RECRUITING

Lyon, France
Centre Léonard de Vinci
RECRUITING

Dechy, France
Centre Marie Curie
RECRUITING

Arras, France
Centre Oscar Lambret
RECRUITING

Lille, France
Centre Paul Strauss
RECRUITING

Strasbourg, France
Centre Pierre Curie
RECRUITING

Beuvry, France
Centre de Radiothérapie de Seine-et-Marne
RECRUITING

Melun, France
Clinique Mutualiste de l'Estuaire
RECRUITING

Saint-Nazaire, France
Clinique Tivoli Ducos
RECRUITING

Bordeaux, France
Clinique Victor Hugo
RECRUITING

Le Mans, France
Gustave Roussy
RECRUITING

Villejuif, France
ICO Nantes Saint Herblain
RECRUITING

Saint-Herblain, France
Institut Godinot
RECRUITING

Reims, France
Institut de Cancérologie de Lorraine
RECRUITING

Vandœuvre-lès-Nancy, France
Maastro
RECRUITING

Maastricht, Netherlands
ROC 37
RECRUITING

Chambray-lès-Tours, France