AI predicts lymphedema risk to guide breast cancer radiation decisions

NCT ID NCT07187726

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether an artificial intelligence tool can predict a breast cancer patient's risk of developing arm lymphedema (swelling) after radiation therapy. About 724 women will be randomly assigned to either see their personalized risk prediction or not. The goal is to see if knowing this risk helps patients and doctors choose safer radiation options, reducing side effects and improving quality of life over two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AI-based risk prediction tool (XAINET)

What this could lead to

If successful, this could help breast cancer patients and doctors make more informed decisions about radiotherapy, potentially reducing arm swelling and improving quality of life.

What could go wrong

This is a study about communication, not a new treatment. The AI tool's predictions may not be accurate for everyone, and the trial is still recruiting, so results are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast neoplasm invasive breast carcinoma Unilateral Breast Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH Lyon Sud

    RECRUITING

    Oullins, France

    Contact

  • CH de Saint Quentin

    RECRUITING

    Saint-Quentin, France

    Contact

  • CHD Vendée

    RECRUITING

    La Roche-sur-Yon, France

    Contact

  • CHI Créteil

    RECRUITING

    Créteil, France

    Contact

  • CHU Sud La Réunion

    RECRUITING

    Saint-Pierre, France

    Contact

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, France

  • Centre François Baclesse

    RECRUITING

    Caen, France

    Contact

  • Centre Georges François Leclerc

    RECRUITING

    Dijon, France

    Contact

  • Centre Guillaume Le Conquérant

    RECRUITING

    Le Havre, France

    Contact

  • Centre Henri Becquerel

    RECRUITING

    Rouen, France

    Contact

  • Centre Jean Perrin

    RECRUITING

    Clermont-Ferrand, France

    Contact

  • Centre Léon Bérard

    RECRUITING

    Lyon, France

    Contact

  • Centre Léonard de Vinci

    RECRUITING

    Dechy, France

    Contact

  • Centre Marie Curie

    RECRUITING

    Arras, France

    Contact

  • Centre Oscar Lambret

    RECRUITING

    Lille, France

    Contact

  • Centre Paul Strauss

    RECRUITING

    Strasbourg, France

    Contact

  • Centre Pierre Curie

    RECRUITING

    Beuvry, France

    Contact

  • Centre de Radiothérapie de Seine-et-Marne

    RECRUITING

    Melun, France

    Contact

  • Clinique Mutualiste de l'Estuaire

    RECRUITING

    Saint-Nazaire, France

    Contact

  • Clinique Tivoli Ducos

    RECRUITING

    Bordeaux, France

    Contact

  • Clinique Victor Hugo

    RECRUITING

    Le Mans, France

    Contact

  • Gustave Roussy

    RECRUITING

    Villejuif, France

    Contact

  • ICO Nantes Saint Herblain

    RECRUITING

    Saint-Herblain, France

    Contact

  • Institut Godinot

    RECRUITING

    Reims, France

    Contact

  • Institut de Cancérologie de Lorraine

    RECRUITING

    Vandœuvre-lès-Nancy, France

    Contact

  • Maastro

    RECRUITING

    Maastricht, Netherlands

    Contact

  • ROC 37

    RECRUITING

    Chambray-lès-Tours, France

    Contact