AI may help decide who benefits from Clot-Busting procedure

NCT ID NCT07181083

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether an AI model can predict if a clot-removal procedure will work for people with severe deep vein thrombosis (DVT) in the leg. Thirty adults will receive a catheter-based treatment that breaks up and removes clots, and the AI will analyze MRI scans to see if it can forecast recovery. The goal is to help doctors avoid giving this invasive treatment to patients who are unlikely to benefit, reducing risks like kidney damage and bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rtPA (a clot-dissolving drug) delivered via the AngioJet ZelanteDVT catheter

What this could lead to

If successful, this AI model could help doctors choose which patients with deep vein thrombosis will benefit most from clot-removal procedures, avoiding unnecessary risks.

What could go wrong

This is a small, early study with only 30 participants, so the AI model may not work well for all patients. The procedure itself carries risks like kidney injury and bleeding.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Venous Thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rajaie Cardiovascular Medical and Research Institute

    Tehran, Tehran Province, 1995614331, Iran