AI boosts Low-Dose brain scans, cutting contrast agent by up to 90%

NCT ID NCT06224543

First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 35 times

Summary

This study tested whether artificial intelligence (AI) can enhance brain MRI images taken with a much lower dose of gadobutrol contrast agent, making them as clear as standard-dose images. Sixty adults with known or suspected brain lesions received either a low dose (10% or 25% of the standard) or the standard dose. The AI software then boosted the low-dose images. The goal was to see if the AI-enhanced low-dose images are non-inferior to standard-dose images, potentially reducing patients' exposure to contrast agents.

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Contacts and locations

Locations

  • Central Illinois Radiological Associates; OSF St. Francis Hospital Peoria

    Peoria, Illinois, 61637, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • The Pennsylvania State University

    State College, Pennsylvania, 16801, United States

  • UMass Chan Medical School

    Worcester, Massachusetts, 01655, United States

Conditions

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