Doctors repurpose HIV drugs in bid to calm rare child brain disease

This study tested whether three medications commonly used to treat HIV could help children with Aicardi-Goutières syndrome (AGS), a rare genetic disorder that causes brain inflammation. Eleven children received the drug combination for one year to see if it could reduce the overactive immune response that damages their nervous system. The main goal was to measure changes in a specific immune system marker, not to cure the disease, as ongoing treatment would likely be needed.