New natural gel could soothe heartburn without Long-Term drug risks

NCT ID NCT06984484

Recruiting now Symptom relief Sponsor: Devintec Sagl Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether Afluxin®, a natural gel made from tamarind seed, pea protein, and polyacrylic acid, can reduce heartburn and regurgitation in people with mild-to-moderate GERD. About 208 adults will take the gel or an inactive placebo three times daily for 7 days. The goal is to see if Afluxin® provides faster symptom relief than placebo, offering a potential alternative to long-term acid-reducing drugs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Afluxin® (a mix of tamarind seed polysaccharide, pea protein, and polyacrylic acid)
What this could lead to: If it works, this could offer a natural, short-term option for people with mild-to-moderate GERD who want to avoid long-term side effects of standard acid-reducing drugs.
What could go wrong: This is a small, early-stage trial (208 people) testing only 7 days of treatment. The results may not apply to severe GERD or long-term use, and the placebo group may also improve.

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Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROESOPHAGEAL REFLUX DISEASE (GERD)

Contacts and locations

Locations

A.O.U. Città della Salute e della Scienza di Torino
RECRUITING

Torino, 10126, Italy
AOU Federico II di Napoli
RECRUITING

Naples, 80131, Italy
Azienda Ospedale Università Padova
RECRUITING

Padova, 35128, Italy
Humanitas Research Hospital
RECRUITING

Rozzano (MI), 20089, Italy
IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation
RECRUITING

Milan, 20122, Italy
IRCCS Policlinico San Martino
RECRUITING

Genova, 16132, Italy
S. Andrea Ospedale Universitario
RECRUITING

Roma, 00189, Italy

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