New natural gel could soothe heartburn without Long-Term drug risks
NCT ID NCT06984484
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether Afluxin®, a natural gel made from tamarind seed, pea protein, and polyacrylic acid, can reduce heartburn and regurgitation in people with mild-to-moderate GERD. About 208 adults will take the gel or an inactive placebo three times daily for 7 days. The goal is to see if Afluxin® provides faster symptom relief than placebo, offering a potential alternative to long-term acid-reducing drugs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Afluxin® (a mix of tamarind seed polysaccharide, pea protein, and polyacrylic acid)
What this could lead to
If it works, this could offer a natural, short-term option for people with mild-to-moderate GERD who want to avoid long-term side effects of standard acid-reducing drugs.
What could go wrong
This is a small, early-stage trial (208 people) testing only 7 days of treatment. The results may not apply to severe GERD or long-term use, and the placebo group may also improve.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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A.O.U. Città della Salute e della Scienza di Torino
RECRUITINGTorino, 10126, Italy
Contact
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AOU Federico II di Napoli
RECRUITINGNaples, 80131, Italy
Contact
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Azienda Ospedale Università Padova
RECRUITINGPadova, 35128, Italy
Contact
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Humanitas Research Hospital
RECRUITINGRozzano (MI), 20089, Italy
Contact
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IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation
RECRUITINGMilan, 20122, Italy
Contact
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IRCCS Policlinico San Martino
RECRUITINGGenova, 16132, Italy
Contact
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S. Andrea Ospedale Universitario
RECRUITINGRoma, 00189, Italy
Contact