Eye drug trial for rare macular disease stops early – only 16 patients enrolled

NCT ID NCT03845049

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tested aflibercept (Eylea) eye injections against placebo in 16 people with macular telangiectasia type 1, a rare condition that causes vision loss. The study aimed to see if aflibercept could reduce swelling in the macula. However, the trial was terminated early, so the results are limited and not conclusive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

aflibercept (Eylea) eye injection

What this could lead to

If it works, this could point toward a treatment for vision loss from macular telangiectasia type 1.

What could go wrong

The trial was terminated early with only 16 participants, so results are very limited. It is unclear if aflibercept is better than placebo for this rare condition.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

macular telangiectasia macular telangiectasia type 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU dijon Bourgogne

    Dijon, 21000, France