New hope for kids with severe colitis: drug trial seeks remission

NCT ID NCT07158242

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This study tests a new medicine called afimkibart in children aged 2 to 17 with moderate to severe ulcerative colitis, a chronic bowel disease. The goal is to see if the drug can safely reduce symptoms and lead to remission at 12 and 52 weeks. Participants must have tried other treatments without success. This is a long-term control study, not a cure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrooke's Hospital

    RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

  • Birmingham Children's Hospital

    RECRUITING

    Birmingham, B4 6NH, United Kingdom

  • Children's Healthcare of Atlanta

    RECRUITING

    Atlanta, Georgia, 30342, United States

  • Chulalongkorn University

    RECRUITING

    Bangkok, 10330, Thailand

  • NYU School of Medicine

    RECRUITING

    New York, New York, 10016, United States

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 100, Taiwan

  • Ramathibodi Hospital

    RECRUITING

    Bangkok, Thailand

  • Sheffield Childrens Hospital

    RECRUITING

    Sheffield, S10 2TH, United Kingdom

  • Siriraj Hospital

    RECRUITING

    Bangkok, 10700, Thailand

Conditions

Explore the condition pages connected to this study.