New antibiotic afabicin tested for tough bone infections – but trial stopped early
NCT ID NCT03723551
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested a new antibiotic called afabicin in 67 people with bone or joint infections caused by staph bacteria. The goal was to see if afabicin is safe and works as well as standard antibiotics. However, the trial was stopped early, so the full results are not available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- afabicin
- What this could lead to
- If successful, afabicin could offer a new antibiotic option for treating stubborn staph infections in bones or joints.
- What could go wrong
- This was a small, early-stage (Phase 2) trial that was terminated, so we don't have complete results. It's unclear if afabicin works better than current treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BONE OR JOINT INFECTION are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Academician Vakhtang Bochorishvili Clinic LTD
Tbilisi, 0160, Georgia
-
Caucasus Medical Center LLC
Tbilisi, 0186, Georgia
-
City Hospital #9 under Zaporizhia City Council
Zaporizhia, 69065, Ukraine
-
Clinical Research Unit, University of Pretoria
Pretoria, 0002, South Africa
-
Dnipropetrovsk Regional Clinical Hospital
Dnipro, 49027, Ukraine
-
Georgian Clinics JSC
Akhalts'ikhe, 0800, Georgia
-
Global Clinical Trials (Pty) Ltd
Pretoria, 0157, South Africa
-
Institute of Traumatology and Orthopedics
Kyiv, 01601, Ukraine
-
Kharkiv Regional Clinical Traumatology Hospital
Kharkiv, 61176, Ukraine
-
Kyiv City Clinical Hospital #8 under the Executive Body of Kyiv City Council (Kyiv City State Administration)
Kyiv, Ukraine
-
Kyiv Regional Clinical Hospital
Kyiv, 04107, Ukraine
-
LEPL The First University Clinic of Tbilisi State Medical University
Tbilisi, 0141, Georgia
-
Lviv Regional Hospital of Veterans of Wars and Repressed after Yurii Lypa
Vynnyky, 79495, Ukraine
-
Malkhaz Katsiashvili Multiprofile Emergency Medicine Center LLC
Tbilisi, 0101, Georgia
-
Regional Clinical Hospital under Ivano-Frankivsk Regional Council
Ivano-Frankivsk, 76008, Ukraine
-
Tbilisi State Medical University And Ingorokva High Medical Technology University Clinic LLC
Tbilisi, 0144, Georgia
-
Vinnytsya Regional Clinical Hospital
Vinnytsia, 21028, Ukraine
-
West Georgia Medical Center LLC
Kutaisi, 4600, Georgia
-
Worthwhile Clinical Trials, Lakeview Hospital
Benoni, 1500, South Africa