New shot aims to save sight in dry macular degeneration

NCT ID NCT06990269

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 41 times

Summary

This study tests an investigational drug called ADX-038 in 240 people with geographic atrophy, an advanced form of dry age-related macular degeneration that causes blind spots. The drug is given as a shot under the skin and is compared to a placebo to see if it can slow the loss of a key layer in the retina over 12 months. Participants must have a certain size of retinal damage and be willing to receive required vaccinations.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ADARx Clinical Site

    RECRUITING

    Gilbert, Arizona, 85297, United States

  • ADARx Clinical Site

    RECRUITING

    Phoenix, Arizona, 85020, United States

  • ADARx Clinical Site

    RECRUITING

    Beverly Hills, California, 90211, United States

  • ADARx Clinical Site

    RECRUITING

    Huntington Beach, California, 93647, United States

  • ADARx Clinical Site

    RECRUITING

    Poway, California, 92064, United States

  • ADARx Clinical Site

    RECRUITING

    Orlando, Florida, 32806, United States

  • ADARx Clinical Site

    RECRUITING

    Wildwood, Florida, 34785, United States

  • ADARx Clinical Site

    RECRUITING

    Hagerstown, Maryland, 21740, United States

  • ADARx Clinical Site

    RECRUITING

    Reno, Nevada, 89502, United States

  • ADARx Clinical Site

    RECRUITING

    Erie, Pennsylvania, 16505, United States

  • ADARx Clinical Site

    RECRUITING

    Austin, Texas, 78705, United States

  • ADARx Clinical Site

    RECRUITING

    Dallas, Texas, 75231, United States

  • ADARx Clinical Site

    RECRUITING

    McAllen, Texas, 78503, United States

  • ADARx Clinical Site

    RECRUITING

    Round Rock, Texas, 78681, United States

  • ADARx Clinical Site

    RECRUITING

    San Antonio, Texas, 78340, United States

  • ADARx Clinical Site

    RECRUITING

    The Woodlands, Texas, 77384, United States

  • ADARx Clinical Site

    RECRUITING

    St. George, Utah, 84790, United States

  • ADARx Clinical Site

    RECRUITING

    Albury, New South Wales, 2640, Australia

  • ADARx Clinical Site

    RECRUITING

    Hurstville, New South Wales, 2220, Australia

  • ADARx Clinical Site

    RECRUITING

    Parramatta, New South Wales, 2150, Australia

  • ADARx Clinical Site

    RECRUITING

    East Melbourne, Victoria, 3002, Australia

  • ADARx Clinical Site

    RECRUITING

    Rowville, Victoria, 3178, Australia

  • ADARx Clinical Site

    RECRUITING

    Ottawa, Ontario, K2B 7E9, Canada

  • ADARx Clinical Site

    RECRUITING

    Toronto, Ontario, M8X 2X3, Canada

Conditions

Explore the condition pages connected to this study.