New combo therapy shows promise for tough colorectal cancer

NCT ID NCT03290937

First seen Nov 03, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This early-phase trial tested a combination of two antibody drugs (utomilumab and cetuximab) plus chemotherapy (irinotecan) in 34 people with advanced colorectal cancer that had spread. The main goals were to find the safest dose and see if the tumors shrank. The study is complete, and results help guide future research.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.