Brain zap test may tailor ADHD meds for kids

NCT ID NCT04421248

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to see if two brain measurements taken with Transcranial Magnetic Stimulation (TMS) can help guide ADHD treatment in children aged 8 to 12. Researchers will test these measurements for reliability, how they change with a single dose of methylphenidate (Ritalin), and how they relate to thinking and emotion. The goal is to develop a tool that could lead to more personalized and effective ADHD care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Methylphenidate (Ritalin)

What this could lead to

If successful, this could lead to a brain-based test to help doctors choose the best ADHD treatment for each child, improving outcomes.

What could go wrong

This is an early-phase biomarker study, not a treatment trial. The TMS measures may not reliably predict treatment response, and results may not apply to all children with ADHD.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

attention deficit-hyperactivity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kennedy Krieger Institute

    RECRUITING

    Baltimore, Maryland, 21205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••