New drug duo takes on advanced cancers

NCT ID NCT05405595

First seen Jan 11, 2026 · Last updated May 08, 2026 · Updated 20 times

Summary

This study tests a new drug called ADG126 combined with an existing immunotherapy (pembrolizumab) in people with advanced or metastatic solid tumors. The goal is to find the safest and most effective dose and see if the combination can shrink tumors. About 186 adults with various solid cancers will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

    Contact

    Contact

  • CHA Bundang Medical Center, CHA university

    RECRUITING

    Seongnam, Gyeonggido, 13496, South Korea

    Contact

    Contact

  • Chungbuk National University Hospital

    RECRUITING

    Cheongju-si, North Chungcheong, 28644, South Korea

    Contact

    Contact

  • City of Hope National Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact

    Contact

  • City of Hope Orange County

    RECRUITING

    Irvine, California, 92618, United States

    Contact

  • Dong -A University Hospital

    TERMINATED

    Seogu, Busan Gwangyeogsi, 49201, South Korea

  • Florida cancer specialist/Sarah Cannon Research Institute

    ACTIVE_NOT_RECRUITING

    Sarasota, Florida, 34232, United States

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact

  • Fujian Cancer Hospital

    RECRUITING

    Fuzhou, Fujian, China

    Contact

  • Hong Kong Humanity & Health Clinical Trial Center

    RECRUITING

    Hong Kong, Hong Kong, China

    Contact

  • Honor Health Research Institute

    RECRUITING

    Scottsdale, Arizona, 85251, United States

    Contact

  • KangBuk Samsung Hospital

    TERMINATED

    Seoul, 03081, South Korea

  • Keimyung University Dongsan Hospital

    TERMINATED

    Daegu, 41931, South Korea

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact

  • Prince of Wales Hospital

    RECRUITING

    Hong Kong, Hong Kong, China

    Contact

  • Samsung Medical Center

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 06351, South Korea

    Contact

    Contact

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

    Contact

    Contact

  • Severance Hospital Yonsei University Health System

    RECRUITING

    Seoul, 3722, South Korea

    Contact

    Contact

  • SunYat-Sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • The Catholic University of Korea Street. Vincent Hospital

    TERMINATED

    Suwon, Gyeonggido, 16247, South Korea

  • The Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195-0001, United States

    Contact

Conditions

Explore the condition pages connected to this study.