New drug cocktail aims to shrink rectal tumors before surgery

NCT ID NCT07454720

First seen Mar 19, 2026 · Last updated May 16, 2026 · Updated 6 times

Summary

This study tests whether adding two experimental drugs (adebrelimab and SHR-8068) to standard chemoradiation helps shrink locally advanced rectal cancer before surgery. About 165 adults aged 18-75 with resectable tumors who haven't had prior treatment will participate. The main goal is to see if the cancer completely disappears after treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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