New drug combo aims to shrink rectal tumors before surgery

NCT ID NCT07454720

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding two drugs (adebrelimab and SHR-8068) to standard chemoradiation helps shrink advanced rectal cancer before surgery. About 165 adults aged 18-75 with resectable tumors will participate. The goal is to see if more patients achieve a complete response (no cancer detectable) after treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430022, China

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310022, China