Experimental antibody drug tested for Tough-to-Treat leukemia

NCT ID NCT03698552

First seen Nov 03, 2025 · Last updated May 15, 2026 · Updated 28 times

Summary

This study tested a new drug called ADCT-602 in 37 people with a type of blood cancer (B-cell acute lymphoblastic leukemia) that had returned or stopped responding to other treatments. The drug is a lab-made antibody designed to attach to a protein (CD22) on cancer cells and stop them from growing. The study was stopped early, but it aimed to find the safest dose and see how well the drug worked.

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Contacts and locations

Locations

  • City of Hope Comprehensive Cancer

    Monrovia, California, 91016, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.