Cream vs. freeze: new study tests easier treatment for stubborn foot warts

NCT ID NCT07016360

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two treatments for recurrent plantar warts: a topical adapalene gel (a type of retinoid cream) and cryotherapy (freezing with liquid nitrogen). Researchers will enroll 98 adults aged 18-60 with recurring warts on the soles of their feet. The goal is to see which treatment clears the warts more completely after 8 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Adapalene gel 0.1% and liquid nitrogen cryotherapy

What this could lead to

If adapalene works as well as cryotherapy, it could offer a less painful, at-home treatment option for stubborn plantar warts.

What could go wrong

This is a small, single-center trial with only 98 participants. Results may not apply to everyone, and adapalene might be less effective than cryotherapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

common wart plantar wart

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Khyber Teaching Hospital

    RECRUITING

    Peshawar, Khyber Pakhtunkhwa, 25000, Pakistan