Cream vs. freeze: new study tests easier treatment for stubborn foot warts
NCT ID NCT07016360
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two treatments for recurrent plantar warts: a topical adapalene gel (a type of retinoid cream) and cryotherapy (freezing with liquid nitrogen). Researchers will enroll 98 adults aged 18-60 with recurring warts on the soles of their feet. The goal is to see which treatment clears the warts more completely after 8 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Adapalene gel 0.1% and liquid nitrogen cryotherapy
- What this could lead to
- If adapalene works as well as cryotherapy, it could offer a less painful, at-home treatment option for stubborn plantar warts.
- What could go wrong
- This is a small, single-center trial with only 98 participants. Results may not apply to everyone, and adapalene might be less effective than cryotherapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Khyber Teaching Hospital
RECRUITINGPeshawar, Khyber Pakhtunkhwa, 25000, Pakistan