New drug tested for tough cancers

NCT ID NCT06336148

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tested a new drug called ACTM-838 in 10 people with advanced solid tumors that no longer responded to standard treatments. The main goals were to check safety and find the right dose. The study was stopped early, so results are limited.

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Conditions

The condition(s) this trial relates to.

bile duct neoplasm breast neoplasm cholangiocarcinoma colorectal neoplasm Esophageal Neoplasms gastric neoplasm Head and Neck Neoplasms melanoma mesothelioma neoplasm non-small cell lung carcinoma ovarian cancer pancreatic neoplasm renal cell carcinoma sarcoma Thyroid Neoplasms Urinary Bladder Neoplasms Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alfred Hospital, 55 Commercial Road, Site No: 201

    Melbourne, Victoria, 3004, Australia

  • Southern Oncology Clinical Research Unit, Level 3, Mark Oliphant Building, 5 Laffer Drive, Site No: 202

    Bedford Park, South Australia, 5042, Australia

  • UPMC Hillman Cancer Center, 5115 Centre Ave

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Southern California Norris Comprehensive Cancer Center, 1441 Eastlake Ave.

    Los Angeles, California, 90033, United States

  • Westmead Hospital, Cnr Hawkesbury Road and Darcy Road, Site No: 200

    Westmead, New South Wales, 2145, Australia