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Can a global patient registry improve anal cancer care for people with HIV?

NCT ID NCT05328765

Knowledge-focused Sponsor: Latin American Cooperative Oncology Group Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 28, 2026 · Last updated Aug 28, 2026

Summary

This study builds a global registry of adults with anal squamous cell carcinoma, both with and without HIV infection. Researchers will collect real-world data on treatments, lab results, and outcomes to compare how the disease progresses in each group. The goal is to identify factors that influence survival and treatment response, which could guide better care for people living with HIV.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this registry could reveal which treatments work best for anal cancer in people with HIV, improving care and survival.
What could go wrong
This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may be limited by incomplete data or differences between patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

369 people

The number who actually took part.

Started

Jun 2023

Finished

Feb 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Potentially eligible patients will be screened through the administrative lists of participating centres. Based on convenience and viability, we estimate to accumulate 300 patients with CCA with and without HIV infection.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients 18 years of age or older * Confirmed histological diagnosis of anal canal squamous cell carcinoma. Basaloid subtype is accepted * Have underundered serological test for HIV infection * Any clinical stage Exclusion Criteria: * Lack of data on treatments and clinical outcomes

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Conditions

The condition(s) this trial relates to.

anal squamous cell carcinoma anus neoplasm HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anal squamous cell carcinoma HIV infections

Contacts and locations

Locations

  • A.C. Camargo Cancer Center

    São Paulo, São Paulo, 01509-001, Brazil

  • CEPON - Centro de Pesquisas Oncológicas

    Florianópolis, Santa Catarina, 88034-000, Brazil

  • HUOL - Hospital Universitário Onofre Lopes da UFRN

    Natal, Rio Grande do Norte, 59012-300, Brazil

  • Hospital de Amor de Barretos

    Barretos, São Paulo, 14784-400, Brazil

  • Hospital de Clínicas de Montevideo Dr. Manuel Quintela

    Montevideo, Uruguai, Uruguay

  • Hospital de Gastroenterología Carlos Bonorino Udaondo

    Buenos Aires, Buenos Aires, Argentina

  • INCA - Instituto Nacional de Câncer

    Rio de Janeiro, Rio de Janeiro, 20230-130, Brazil

  • INCan - Instituto Nacional de Cancerología

    Mexico City, Mexico City, Mexico

  • INEN - Instituto Nacional de Enfermedades Neoplásicas

    Lima, Peru, Peru

  • Liga Norte Riograndense Contra o Câncer

    Natal, Rio Grande do Norte, 59062-000, Brazil

  • Oncosalud AUNA

    Lima, Peru, Peru

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