New hope for kids with devastating brain cancer

NCT ID NCT06838676

Summary

This study is testing an oral medication called ACT001 in children and young adults with two types of aggressive brain tumors: diffuse intrinsic pontine glioma (DIPG) and H3K27-altered high-grade glioma (HGG). The main goals are to see if the drug is safe and if it helps patients live longer or shrink their tumors. Participants will take the drug in 28-day cycles for up to two years if they are benefiting from it.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • C.S. Mott Children's Hospital

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital of Philidelphia

    NOT_YET_RECRUITING

    Philidelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's National Medical Center

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cincinnati Children's Hospital

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Medical Center

    NOT_YET_RECRUITING

    Durham, North Carolina, 27708, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Emory University/Children's Healthcare of Atlanta

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopp Children's Cancer Center at NCT Heidelberg (KiTZ)

    NOT_YET_RECRUITING

    Heidelberg, Baden-Wurttemberg, 69120, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montreal Children's Hospital

    NOT_YET_RECRUITING

    Montreal, Quebec, H4A3J1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nicklaus Children's Hospital

    NOT_YET_RECRUITING

    Miami, Florida, 33155, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Perth Children's Hospital

    NOT_YET_RECRUITING

    Perth, Western Australia, 6000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Queensland Children's Hospital

    NOT_YET_RECRUITING

    South Brisbane, Queensland, 4101, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Children's Hospital

    NOT_YET_RECRUITING

    Melbourne, Victoria, 3052, Australia

    Contact Email: •••••@•••••

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Louis Children's Hospital

    NOT_YET_RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Starship Children's Hospital

    NOT_YET_RECRUITING

    Auckland, Grafton, 1023, New Zealand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sydney Children's Hospital

    NOT_YET_RECRUITING

    Randwick, New South Wales, 2031, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Hospital for Sick Children (SickKids)

    NOT_YET_RECRUITING

    Toronto, Ontario, M5G1X8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.