Can talking therapy boost recovery after stem cell transplants?
NCT ID NCT07516314
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a type of talk therapy called Acceptance and Commitment Therapy (ACT) for people getting stem cell transplants. The goal is to help patients and their caregivers stick with physical activity and healthy eating during a tough recovery. Researchers will measure if it improves physical function, hospital stay length, and survival in 476 participants.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Acceptance and Commitment Therapy (ACT) sessions
- What this could lead to
- If it works, this could help stem cell transplant patients maintain physical function and reduce complications during recovery.
- What could go wrong
- This is a phase 2 trial, so results are still uncertain. The therapy may not improve physical function or survival, and it requires patient and caregiver commitment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 476 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
May 2026
An estimate. Start dates often move.
- Expected to finish
-
Apr 2031
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Patient Inclusion Criteria: * Ability of participant to understand this study, and participant willingness to sign a written informed consent. NOTE: Remote / electronic consent via REDCap consenting allowed per IRB policy and approval. * Stated willingness to comply with all study procedures and lifestyle considerations and availability for the duration of the study * Plan to undergo allogeneic HCT in approximately 30 days * Males and/or females age 18 - 80 years * Agreement to adhere to Lifestyle Considerations throughout study duration * Access to necessary resources for participating in a technology-based intervention (i.e., computer, smartphone, internet access). NOTE: A smartphone will be provided to participants if needed. * Able to read/write English or Spanish (as we lack trained ACT interventionists in other languages) Caregiver Inclusion Criteria: * Ability of participant to understand this study, and participant willingness to sign a written informed consent. NOTE: Remote / electronic consent via REDCap consenting allowed per IRB policy and approval. * Stated willingness to comply with all study procedures and lifestyle considerations and availability for the duration of the study * Males and/or females age 18-80 years * Agreement to adhere to Lifestyle Considerations throughout study duration * Access to necessary resources for participating in a technology-based intervention (i.e., computer, smartphone, internet access). NOTE: A smartphone will be provided to participants if needed. * Able to read/write English or Spanish (as we lack trained ACT interventionists in other languages) Patient Exclusion Criteria: * Caregiver unwilling to enroll (as standard of care, all HCT patients are required to have a caregiver, but caregivers may decline to participate in this study which would make the patient ineligible for this study) * Diagnosed with a psychiatric illness or is in a social situation that would limit compliance with study requirements * Concurrent participation in another behavioral intervention research study. * Activity restrictions that limit one's ability to engage in intense physical activity Caregiver Exclusion Criteria: * Patient unwilling to enroll * Diagnosed with a psychiatric illness or is in a social situation that would limit compliance with study requirements • Concurrent participation in another behavioral intervention research study. * Activity restrictions that limit one's ability to engage in intense physical activity
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Stem cell transplant patients are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
2 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Duke University
Durham, North Carolina, 27705, United States
-
University of Kansas Cancer Center
Kansas City, Kansas, 66160, United States