New hope for rare bleeding disorder: safer combo shows promise

NCT ID NCT03384277

First seen Feb 28, 2026 · Last updated May 14, 2026 · Updated 13 times

Summary

This study tested two treatments for acquired hemophilia A, a rare condition where the immune system attacks clotting factors, causing severe bleeding. 66 adults received either steroids with cyclophosphamide or steroids with a single dose of rituximab. The goal was to see which combination better eliminates harmful antibodies and controls bleeding, with fewer side effects.

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Contacts and locations

Locations

  • Ethics Committee of Blood disease hospital, Chinese Academy of Medical Sciences

    Tianjin, Tianjin Municipality, 300020, China

Conditions

Explore the condition pages connected to this study.