Promising combo tackles nerve pain in rare blood cancers
NCT ID NCT05065554
First seen Jan 11, 2026 · Last updated Apr 28, 2026 · Updated 15 times
Summary
This study tests whether combining acalabrutinib with rituximab can safely reduce nerve damage symptoms in people with IgM MGUS or Waldenstrom macroglobulinemia. The goal is to lower abnormal IgM protein levels that attack nerves. Twelve adults with confirmed IgM-related neuropathy are enrolled, and the study is active but no longer recruiting.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02214, United States
Conditions
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