Heart-Safe CLL treatment? study switches patients to acalabrutinib

NCT ID NCT06757647

First seen Nov 12, 2025 · Last updated May 13, 2026 · Updated 22 times

Summary

This study tests whether acalabrutinib, a targeted cancer drug, can control chronic lymphocytic leukemia (CLL) without the heart side effects often caused by a similar drug, ibrutinib. About 61 adults with CLL who had heart problems on ibrutinib will switch to acalabrutinib. Researchers will use heart MRIs to check if heart function improves or stays stable, while also monitoring how well the cancer is controlled.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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