Inhaled anxiety drug may lower abuse risk, early study hints
NCT ID NCT00603980
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared the abuse potential of an inhaled version of alprazolam (Staccato) with the standard oral pill in 31 people who had previously abused sedatives. Participants rated how much they liked each form and whether they would take it again. The goal was to see if the inhaled form might be less addictive. Results are preliminary and from a small group, so more research is needed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
alprazolam (inhaler and oral pill)
What this could lead to
If successful, this could lead to a less addictive way to deliver alprazolam for anxiety or panic attacks.
What could go wrong
This is a small, early-phase study in people with a history of sedative abuse, so results may not apply to the general population. The inhaled form may still carry abuse potential.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Johns Hopkins University School of Medicine
Baltimore, Maryland, 21224, United States