New epilepsy drug candidate enters first human safety tests

NCT ID NCT07156201

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-stage trial is testing a new drug called ABS-1230 in 74 healthy adults to see if it is safe and how the body processes it. The drug is being developed for a rare type of epilepsy caused by changes in the KCNT1 gene. Participants will receive either the drug or a placebo, and researchers will monitor for side effects and measure drug levels in the blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ABS-1230

What this could lead to

If this trial shows ABS-1230 is safe, it could pave the way for testing it as a treatment for KCNT1-related epilepsy.

What could go wrong

This is a very early, small study in healthy people, not patients. It only looks at safety and how the drug moves through the body, not whether it works for epilepsy. Many drugs fail at this stage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

developmental and epileptic encephalopathy, 14

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Scientia Clinical Research

    RECRUITING

    Sydney, New South Wales, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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