Gene therapy trial aims to tame rare kidney stone disease
NCT ID NCT06839235
First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 25 times
Summary
This early-stage study tests a new gene therapy called ABO-101 for people with primary hyperoxaluria type 1 (PH1), a rare genetic condition that causes painful kidney stones and kidney damage. The trial will first give a single dose to adults to find the safest amount, then test that dose in children. The main goal is to check safety and see if the treatment can lower oxalate levels in urine, which may help control the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Heidi Chaker
RECRUITINGSfax, Tunisia
Contact Phone: •••-•••-••••
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Hospices Civils de Lyon- Hôpital Femmes Mères Enfants
NOT_YET_RECRUITINGLyon, France
Contact Phone: •••-•••-••••
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Kindernierenzentrum Bonn
NOT_YET_RECRUITINGBonn, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-••••
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Nucleus Network
WITHDRAWNSaint Paul, Minnesota, 55114, United States
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Queen Elizabeth Hospital Birmingham
RECRUITINGBirmingham, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Royal Free Hospital
RECRUITINGLondon, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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