New pill aims to tame genital herpes outbreaks

NCT ID NCT06698575

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests an experimental drug called ABI-1179 in healthy volunteers and people with recurrent genital herpes caused by HSV-2. The main goal is to check safety and how the body processes the drug. Researchers will give single or multiple doses and monitor for side effects. This is a first step to see if the drug is safe enough for larger trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ABI-1179 (an experimental antiviral drug taken as a tablet)

What this could lead to

If this early study shows the drug is safe and well-tolerated, it could pave the way for a new treatment option to reduce herpes outbreaks.

What could go wrong

This is a very early Phase 1 trial focused on safety and dosing, not on whether the drug actually works. Many drugs fail in later stages, so there is no guarantee this will become a treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

genital herpes genital herpes simplex type 2 infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alliance for Multispecialty Research

    Kansas City, Missouri, 64114, United States

  • Canopy Clinical Wollongong

    Wollongong, Australia, 2500, Australia

  • East Sydney Doctors

    Darlinghurst, Australia, 2010, Australia

  • Momentum Clinical Research

    Sydney, Australia, 2010, Australia

  • Momentum Kapiti

    Waikanae, New Zealand, 5036, New Zealand

  • Momentum Palmerston North

    Palmerston North, New Zealand, 4414, New Zealand

  • Momentum Sunshine

    Melbourne, Au, 3021, Australia

  • New Zealand Clinical Research

    Auckland, New Zealand, 1010, New Zealand

  • New Zealand Clinical Research

    Christchurch, New Zealand, 8011, New Zealand

  • Pacific Clinical Research Network

    Nelson, New Zealand, 7011, New Zealand

  • Pacific Clinical Research Network

    Rotorua, New Zealand, 3010, New Zealand

  • Pacific Clinical Research Network

    Upper Hutt, New Zealand, 5018, New Zealand

  • Pacific Clinical Research Network

    Hamilton, New, 3200, New Zealand

  • Rochester Clinical Research

    Rochester, New York, 14609, United States

  • Royal Melbourne Hospital

    Parkville, Australia, 3050, Australia

  • Seattle Clinical Research Center

    Seattle, Washington, 98104, United States

  • Taylor Square Private Clinic

    Surry Hills, Australia, 2010, Australia

  • University of Washington Virology Research Clinic

    Seattle, Washington, 98104, United States

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