New combo therapy offers hope for Tough-to-Treat colorectal liver cancer

NCT ID NCT07441369

First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times

Summary

This study tests a combination of the drug abemaciclib with standard chemotherapy (FOLFOX or FOLFIRI) in 16 adults with advanced colorectal cancer that has spread to the liver and hasn't responded to at least two prior treatments. The goal is to see if this combination can shrink tumors and control the disease. Participants will receive the treatment and be monitored for side effects and how long the cancer stays under control.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai Cancer Center

    Shanghai, 200032, China