New drug tested to slow Muscle-Wasting disease

NCT ID NCT05721573

Completed Disease control Sponsor: Abcuro, Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested an investigational drug called ABC008 for adults with inclusion body myositis, a rare muscle-wasting disease. It aimed to see if the drug could safely slow the decline in muscle strength and function compared to a placebo. The trial involved 272 participants and measured changes in their ability to perform daily tasks and muscle strength tests over 76 weeks.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AZ Sint-Lucas & Volkskliniek

Ghent, 9000, Belgium
Austin Neuromuscular Center

Austin, Texas, 78759, United States
Brigham and Womens Hospital

Boston, Massachusetts, 021158, United States
Columbia University Medical Center / The Neurological Institute of New York

New York, New York, 10032, United States
Duke Neurological Disorders Clinic -1L

Durham, North Carolina, 27710, United States
Genge Partners Inc.

Montreal, Quebec, H4A 3T2, Canada
Heritage Medical Research Clinic - University of Calgary

Calgary, Alberta, 3M 1M4, Canada
Hospital Pitie-Salpetriere - AP-HP

Paris, 75013, France
Hospital for Special Surgery

New York, New York, 10021, United States
Johns Hopkins Bayview Medical Center

Baltimore, Maryland, 21224, United States
Johns Hopkins University School of Medicine

Baltimore, Maryland, 21287, United States
Keck Hosptial of USC

Los Angeles, California, 90033, United States
Krankenhaus und Poliklinik Rüdersdorf GmbH

Berlin, 15562, Germany
Mayo Clinic

Jacksonville, Florida, 32224, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Nerve and Muscle Center of Texas

Houston, Texas, 77030, United States
Neuromuscular Diagnostic Center - Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Neuromuscular Research Center

Phoenix, Arizona, 85028, United States
Northwestern Memorial Hospital, Department of Neurology (Clinic)

Chicago, Illinois, 60611, United States
Oregon Health & Science University

Portland, Oregon, 97239, United States
Penn State Health Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
Perron Institute for Neurological and Translational Science

Nedlands, Western Australia, 6009, Australia
Royal Brisbane and Women's Hospital

Herston, Queensland, 4006, Australia
Royal North Shore Hospital

Saint Leonards, New South Wales, 2065, Australia
Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust

Salford, M6 8HD, United Kingdom
Stanford Neuroscience Medical Center

Palo Alto, California, 94304, United States
Texas Neurology

Dallas, Texas, 75206, United States
The Ohio State University Wexner Medical Center

Columbus, Ohio, 43210, United States
UCLA Medical Center

Los Angeles, California, 90095, United States
UPMC Arthritis and Autoimmunity Center, Falk Clinic

Pittsburgh, Pennsylvania, 15213, United States
University College London Hospitals NHS Foundation Trust, National Hospital for Neurology and Neurosurgery (NHNN)

London, WC1N 3BG, United Kingdom
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University Hosptial Duesseldorf

Düsseldorf, 40225, Germany
University of California Irvine Medical Center (UCIMC) - Amyotrophic Lateral Sclerosis (ALS) and Neuromuscular Center

Irvine, California, 92868, United States
University of California, San Francisco

San Francisco, California, 94143, United States
University of Colorado Hospital Anschutz Outpatient Pavillion

Aurora, Colorado, 80045, United States
University of Kansas Medical

Kansas City, Kansas, 66160, United States
University of Nebraska Medical Center

Omaha, Nebraska, 98198, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
University of Washington Medical Center - Montlake

Seattle, Washington, 98195, United States
Virginia Commonwealth University

Henrico, Virginia, 23233, United States
Wake Forrest School of Medicine

Winston-Salem, North Carolina, 27157, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Yale School of Medicine

New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.

INCLUSION BODY MYOSITIS